Ferris Pfeiffer, PhD and James Stannard, MD

Principal Investigators

Ferris Pfeiffer, PhD

Department of Orthopaedic Surgery, Department of Bioengineering

James Stannard, MD

Department of Orthopaedic Surgery

Ferris Pfeiffer, PhD, (left)
and James Stannard, MD

A tapered and an anatomically shaped osteochondral allograft system

Currently, osteochondral allografts (OCA) are used to treat defects in joints resulting from osteochondritis dessicans injury, trauma and osteoarthritis. This encompasses a significant and increasing number of affected patients estimated to be 600,000 to 900,000 per year in the US. In their current form, OCAs are circular cross-section grafts that are easy to create but lack optimal shapes to effectively repair non-circular defects, particularly large ones.

Current standard of care uses these circular grafts in a 'snowman' pattern that consists of overlapping multiple grafts. The associated problems include technical difficulty, poor use of donor tissue, non-anatomical reconstruction and compromised graft stability. The principal investigators are working on a system that makes it possible to repair large OCD defects with a single allograft. The system will be comprised of cutting guides in clinically relevant sizes, a reaming tool to create the socket and a cutting system to create the anatomical graft.

The anatomical OCA system will preserve native tissue better than existing repair instrumentation resulting in faster healing times, improved graft stability and better patient outcomes.

Funded in 2014