The annual grant from the University of Missouri Coulter Translational Partnership (MU Coulter Program) program sponsors collaborative translational research projects that will lead to improvements in patient care.
All projects must include an engineer and clinical collaborator that serve as Co-Principal Investigators (Co-PI’s). All PIs must be from within the UM System. The engineer Co-PI must have a permanent or joint appointment within the School of Engineering and the clinical Co-PI must have a permanent or joint appointment within the School of Medicine, Nursing, Veterinary Medicine or allied health professions and have job responsibilities that include direct contact with patients or patient data.
The research must have a direct application to an important unmet clinical need and the proposed solution, when commercialized, must have a benefit to patients and community health. Proposals are evaluated on the basis of scientific and clinical merit, potential health care impact and significance, experience of the investigators, timeline and pathway to commercialization as well as the likelihood of obtaining the additional funding required to fully translate the proposed solution.
Full Bridge Grant vs. Seed Grant Requests
The MU Coulter Program supports two different kinds of project funding: full and seed. Full proposals are for projects that require ~$100K to complete an experiment that validates the technology or kills the project – i.e., the killer experiment. Full proposal awards fund projects for up to one year. Full projects should be 12-24 months from a commercial event like a license to an established company or professional funding sufficient to continue translation of the technology. The deadline for applying for a 2017 Coulter Bridge Grant has already passed. Watch this space for announcements for 2018.
Seed proposals are for projects that are earlier in nature and that require $25K or less to complete major milestones. Seed projects should be 24-36 months from a commercial event. MU Coulter Seed Grant proposals are accepted all year around.
Full Proposal Submission Guidelines
The full proposal submission process requires submission of a Letter of Intent (LOI). A representative of each team considering submission of an LOI must attend a workshop on how to prepare a Coulter LOI. LOIs are taken through a filtering process that includes a review by the MU Coulter Executive Committee. Teams submitting LOIs that make it through the filtering process are invited to attend the annual Coulter Boot Camp that is now part of MANGMT 8200: Commercialization of Life Science Innovations program. Teams that complete Boot Camp and submit a viable business proposal (see Step 3) are given the opportunity to make the Pitch #1 to the OC for funding of the project. The OC makes the final decision on which projects are selected for funding. The start date for funded projects is July 1.
LOI Submission Guidelines
All investigators considering submission of a Letter of Intent (LOI) must meet with the Coulter Program Office before submitting an LOI. Please contact Cynthia Helphingstine (email: email@example.com or call: 573-882-2709) or Jaya Ghosh (email: firstname.lastname@example.org or call: 573-882-0522) to schedule a meeting. If you have questions about eligibility or if you need to connect with an engineer or clinician, contact the Program Office for assistance. The call for proposals for the 2018 funding cycle is expected to go out in August/September, 2017.
Coulter Boot Camp, now a part of the MANGMT 8200: Commercialization of Life Science Innovations Program
Date: Spring 2018
Time: Each session runs for ~2.5 hours including ~15 min breaks
Food: Refreshments from Columbia restaurants will be served.
The primary objective of the Coulter Boot Camp is to help applicants answer two fundamental questions: 1) Does their envisioned product address a true unmet clinical need? AND 2) Is there a viable business opportunity? The second objective is to help applications develop a pitch deck that best positions their idea for investment and partnerships.
Teams present findings from homework at the start of each session, during which time business advisors will provide real time feedback. Guest lecturers will address topics such as validating the unmet clinical need, determining the value proposition and developing the investor pitch. The Boot Camp and MGMT 8200 uses the Biodesign Handbook, 1st Edition as a guide.
The Spring 2018 MANGMT 8200: Commercialization of Life Science Innovations Program Course Overview will be available shortly. The Spring 2017 MANGMT 8200 Course Overview can be seen here.
Business Proposal Submission
The business Proposal must provide the following information:
- Clinical Context: Does a true unmet clinical need exist?
- Value Proposition: How is your product different from the gold standard and other approaches available on the market?
- Regulatory and Intellectual Property Considerations
- Business Opportunity: Is there sufficient economic incentive to commercialize the envisioned product?
Pitch Day #1
Pitch Day #1 is the team’s opportunity to sell their business case to the Oversight Committee! Project teams will have 10 minutes to present followed by 10 minutes of Q&A.
Research Proposal Submission
The Research Proposal must provide the following information:
- Describe the objectives, rationale, and plan for your Killer Experiment
- What are the activities you will need to perform in order to execute your Killer Experiment? Describe the specific measures and quantitative targets you will use to evaluate performance, progress, and ultimate success
Pitch Day #2
Pitch Day #2 is the team’s opportunity to sell their project to the Oversight Committee and get it funded! Project teams will have 10 minutes to present followed by 10 minutes of Q&A.
Coulter Bridge Grants are awarded for a 12-month period and are renewable. Renewal applications must include a comparison of milestones achieved versus milestones planned in the original submission. Any significant deviations from the original milestone goals must be fully explained. Renewal applications are evaluated on a competitive basis with new applications.